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SIDE EFFECTS

GENOTROPIN is prescribed for the treatment of certain growth disorders. However, as with any medical treatment, GENOTROPIN may cause side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see below for complete Important Safety Information.

GENOTROPIN has different side effects depending on the type of growth disorder it treats. Click on a growth disorder to learn about the side effects related to treating it with GENOTROPIN.

SideEffects

Growth Hormone Deficiency (GHD) in Children

In studies of GENOTROPIN in children with GHD, side effects included injection site reactions, such as pain, redness/swelling, inflammation, bleeding, scarring, lumps, or rash. Other side effects were fat loss, headache, blood in the urine, low thyroid activity, and mildly increased blood sugar.

Small for Gestational Age (SGA)

In studies of GENOTROPIN in children born SGA, side effects included temporarily elevated blood sugar, increased pressure in the brain, early puberty, abnormal jaw growth, injection site reactions, growth of moles, and worsening of scoliosis (curvature of the spine).

Idiopathic Short Stature (ISS)

In studies of GENOTROPIN in children with ISS, side effects included respiratory illnesses, flu, throat infection, inflammation of the nose and throat, stomach pain, headaches, increased appetite, fever, fracture, mood changes, and joint pain.

Prader-Willi Syndrome (PWS)

Deaths have been reported with the use of growth hormone in children with Prader-Willi syndrome. These children were extremely overweight, and had breathing problems and/or lung infection. All patients with Prader-Willi syndrome should be examined for these problems. They should also establish healthy weight control.


In studies of GENOTROPIN in children with PWS, side effects included fluid retention, aggressiveness, joint and muscle pain, hair loss, headache, and increased pressure in the brain.

Turner Syndrome (TS)

TS patients taking growth hormone therapy may be more likely to get ear infections. This is also called otitis media.


In studies of GENOTROPIN in children with Turner syndrome, side effects included flu, throat, ear or sinus infection, runny nose, joint pain, and urinary tract infection.

Growth Hormone Deficiency (GHD) in Adults

In studies of GENOTROPIN in adults with GHD, side effects included fluid retention, joint or muscle pain, stiffness, and changes in sensation. Usually these side effects did not last long and depended on the dose of GENOTROPIN being taken.